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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e32091b5a03c45b4172a6b8ad58668a3b046248b2faedb36df096623f27c66e4' 
  AND token = 'NFXY9Pfa4imSde0FIxIptqLo2XVt3sSreHsjtcwYmaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}