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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5201c1675024eca1f17880e5fbeca8a5ddb4c6e075726f0f237808698fd5ce04' 
  AND token = 'Qt5Ie9QDJGPOA/CzcoeqpeoUQFwBYkEPCzQQn8AG6gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}