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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25ed7e61d6c4f66e004d0b50057b6a2fdb6ee32443665dbcc00737bdf171a7a5' 
  AND token = 'k+DwDwLwKGb1wRvRRQ0s8X2m6kuLledmBZGjYfU5oec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}