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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1728004580d4bd6f0e2949cec36c3628f592b2f13a6bdd4b48abca69246b29f4' 
  AND token = 'tB5MvnuEAReZYNb+nFlA4Op48XIWKWKBCsirY9YzQ64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}