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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '523e1c9ddd2c36bf0412c8c987bf95804bf4b1884b251c6cb32037c8ee8e20c2' 
  AND token = '+TmY+uHGO7U60P1vSZWcrfIS+L8Q/TtvCiDuAah2Fd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}