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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4afec9fb2d15b8bf6eefb278d49f991df0a450d0bf5351418cabd3d6aaf2d789' 
  AND token = '2EI9U0EqDtcia/ZzV2hitUEdfAibuHf00IFBj9a83Mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}