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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce0a50243cabca2b8899d3872203f26f03964014890b4f37d00e3baf0b8dd9cb' 
  AND token = 'WwypSpyxAR0NR4O3hMsq+bt8yyJN/JpHiWt/N2DULKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}