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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81d263461e9bf7293e6a6dad55da9449d6c3b42e24d9efed40433eb1d60a7e1f' 
  AND token = 'ZeWitEFi08SC3QoNoY2KfVWJ62ftl4tqOE5m5NnerE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}