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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4afc7642f2b7a758eefe8f5641cc3ab8ed7bd42ac46c1e0a943665e00b5228b' 
  AND token = 'NfZK00gLcxKbI+TwHNqQ0HWaENsp8RsFao747+SY25w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}