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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74870ec8e3bb709064db4ef04b63863ce7b4138e2081023c2813239816c4609a' 
  AND token = 'SQvFrcA/omU+u8DEUYNtCfhRyG3yk6IR+MGKxG8iYCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}