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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbdddcba31b4121101b3f670cdd555836750a38defd29ae989006648b43017d4' 
  AND token = 'UQITCUDVKKsPCTAziY5NrlBZMeovzI2mt2L38yCjE6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}