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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '215ebbfc0fd23806273fd1a62e5cde457717b5663f0e5c3e0e900991d120be67' 
  AND token = 'seK0GjFy9ILU9gJDIHKo8ruKxbrbh9SnDCUIHpVKCxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}