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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd584e756459f4147239d07ddf50aae7bf29c955121af2121161c24c7a686d4cc' 
  AND token = '5+9XA1VB7m1QCwCTkpnlS/UxiH0s+zvqSPHPMkiRL0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}