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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85cc2b8ed983db827e31a7100aee6267c6d73f79c7e3f7e9168939c0d538497f' 
  AND token = 'Bw3e+w6fl9mzlMbsem2dnke7nV8KOWa7JtXrpRQ91jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}