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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd773a269cb72c661dcac049e3396380be4f27bacdf4f1210452564deb23dd4a' 
  AND token = 'VJg5AwuG+EiVYrtPWusFSKllfjiwOizbfKtliDgceaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}