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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '515859966da0c12ac9f46c20a40b0d4f546116699e3895a7c7e1763853ba4147' 
  AND token = 'Iq4yXX7zQj9169lUDAOymHP+jVTiGS4Uj+TQil0YfZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}