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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b60e13da2a1592c81119f7a8e76c1bb62f32bbfa77356c168b0ecb2c467c7b' 
  AND token = 'DIMhtlVJqqwPx9TrmxAy5v8JhgrPMmPyK4cz42Erswo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}