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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c631d34caf173e7c4f29f8e48c41f7adcefe3efa87c007fd4539c868cd204722' 
  AND token = 'pwQW9k5U1Anf3S+i8A3CeohywUmRjBwNJ1rWiAa1Zzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}