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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78a237eccd09117b79a44a76ce05019b3508e5850ed5882f4900df7a59bad9cc' 
  AND token = '5WyzgRlEOZ6zYy2Li1w+ynVAGfiEGWcvlAH7vK8TmSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}