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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e92d31c38f46064e70cf2075e511879d432f84a7a6d1f89adede8106d4c1f43' 
  AND token = 'e7ZA63ZWjZodZxbi0VgO/we28i10tCifNECRO7R6xPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}