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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c13a4b585f69d1d5b8efc085f8187e6eaa396d259e6e1501ff98c157b52025cf' 
  AND token = 'VPmHF323hV+BfzNyHSk9u6jSWPI+sNV5ubm/3t3j3Rg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}