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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '916f714d646d728cbe2c85489e8520e72c342e31e9653ef337526a99d87fd0fa' 
  AND token = 'nnkLFACsOiFNT9+NIrbiDv2yuZDGU0R3JG/hC1Qe/b0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}