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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c42612f3616ad1d1bde74196d699a405cb606e45f52ee4259feb0b655c02073' 
  AND token = 'fY9Lf15qWKYacitRj122v+S4YiXREPTx+OXOBqMkR6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}