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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '666150b01e486b6df5f7294b24793b0e6e24eb5f73e8b940281e272873879ec5' 
  AND token = 'CSryxsS2hh/8zTu3Gjb/oO5VNHkknFiELeSZ7Yd1HRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}