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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4acf37cf4e50673d2fce9689e4f047742eb07c27c0a97164c077230df85fedcc' 
  AND token = 'eJqCTVapUBcvxG+tp4f1vBOclN5F7z7AEhSmLGDRKc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}