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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bc924e1d56fe9ba475b5c2fdcafaad512757d36a025dbbe3553a8b185cbfa0e' 
  AND token = 'pLX2rU/Vd8IzspUv6YTSdAfvcUnf2Sc0C+MTKpLhf2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}