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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e226f58cf9b094eff989e35f4e4b9101685adf9ca4bafb59858db4a01431f29' 
  AND token = '0Z3abs6rTQ/DTlIoWgv914ZNOzlFhKivnko4u9RngSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}