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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '729e4e48807c1a4e1e16c8e23ee09cf2cb4503437551f35f7fb6248c478c874f' 
  AND token = '4nam4y3eT2+J9ReHeehBYsr+d58YO6Np0d5xOvlwy3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}