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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ffa2cd50c69d97cc58b6d1adf224de70eadae07d0dec9bcbd230b3a6ddafad5' 
  AND token = 'Yo/PPKKZQCb7ExvGajnJYfBg8laK4abkHvOvPkNbEzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}