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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78f702d8e62e06ee49275f74275f5bb99c2cbc810bcc7c22d8ab9b6714d5ab44' 
  AND token = 'nLyRn/GeXPD89nOeBKaO/ciOtm4DEJDYztBVcW/AaIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}