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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24b53134cfeadb41b44470ab3261fb8aa1e945bbd85f48786f3a3fd46462323b' 
  AND token = 'xNsE0M1yDi4hfoK13Q/HdpP/x4lFv2eNf5cVgyGxM3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}