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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '601a37a63f1d67d94c4dd29c462d2534a9116f8135510c4c22e4cb5f274b192d' 
  AND token = 'J7jjRqXCpy6GM5Wy5YY6YlYg9fErdQFbXbhl8+q57cM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}