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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '888353a00d8cd67822379feaa9e6aa24d0d6b8976f9256c1fdb58239299de9ee' 
  AND token = 'X1eiHHpsHz1Nj0oYMLyLsxADT4gjmtIm/SdprflSi/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}