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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b1e5a9413e218ac74c697ffc8502cc0bf595ac11b7deea76da627867d90daaf' 
  AND token = 'LAeVIoh4slEASN5nZiy83ZxWb4Y5aceH58Z0kS7EctI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}