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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64eb6052e67a8282f121a21dbc6ca551e24012ab797cfcc272a0c6a50b47c0b9' 
  AND token = '5SRA2ZzyeAWOwFCXg4Mj9YvEgf01YFIs9SnyaCkpgmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}