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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af9cdc227c7be42608743328dd8eab6a7bb693b85513489c86657d02465bd60c' 
  AND token = 'sd15BDLCPvULDlm7h6GBMl07VFRv0zkEFoNrQijoscc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}