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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1e8e1ece1f4fcc5b030675704d520743a938b17f08fb7a6287faef9c7fdbc7b' 
  AND token = 'H8ycJqhpoD2Hf3Y1T9Mn1/06si4Aob4RkmXY5QtdhZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}