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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '053f212a4e638ad8c1b67ae9a8d96547cad4f9d76db8a095a9b8e5b9179fc96f' 
  AND token = 'VHFuoC8+HAUb5zmbFL8y/hEeWpohAQis/FRJkdPpMiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}