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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a09bbfe79091c4cbd88ceaa74fc2729e7e3cd003b990b60862a5f5fc1034d30' 
  AND token = 'fMM2XRga+U/bYF0B2wdgxKV+tteRl9Ex2pdlDFbpf5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}