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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6afb0fce37d8e469febcb38c199dc5301e07fd32ab666ffc0b3f6a8bab9ffe5f' 
  AND token = 'hNvyaBI2f1/Oirbtl0czi9I3lsz1SeqRK+Qk2NUxYN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}