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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '472361616aaa0ef8c079d12d83f2beeeb07ffb1d6bd69e10c99966102b9bf335' 
  AND token = 'E9uGQuRBbyNeW1Y8eDk2BLTgcmisMyz3bOmfq3Aq6w0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}