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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a539dcc1b33cd843083be459a94b3762866d7f32824c293dbb4ea1616cdebfb' 
  AND token = 'zMEbXPSkkIQe3ykadE5cxL5MmgvAaNRIW3tcNiRru9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}