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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '478743a08807973fb4fa3fca82aff2d09f33129e8335f65eba573fdaa6e29079' 
  AND token = 'uOT2/m7pCr39djFZt8kIVPVVtdQvRtPvDIvF6otbZGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}