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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5807ed7dc354810c392d2743b2fa6c7d912e8387a1e73fc89a8a28ab796c8f9' 
  AND token = 'JEmFvu+9F4b46v2BM3A2F/T2dWKa4LO+n7eSKk0jbZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}