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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80b40bc8907284bcb655563abc292adcff796b265e4c487ce3b8021c48596c5c' 
  AND token = 'l9cCKg/uPRuu/+EXYa+AC6W5ffBZoYMGnPyLQX7KCB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}