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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd108abd6012d57853fa9cc0f370e73642850dbd119c69e08a69bb76dc1a484ad' 
  AND token = 'JGXODWCKUYGUiLIbTWu7nSnFwts9vEM8z2I1PfGNvpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}