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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca1261d657d80c38285487e1671be0f9448d0a0091a823539a3402e32cc23cda' 
  AND token = 'I2TWBKcngeJW9TA/4WlOUYeLnEhPEqSobO92oNrj1Kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}