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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed810d9b632e4af59045122c8a7fd01f967e915edb79bf6aa4d1a8530fd1cb81' 
  AND token = 'q+WM8Ik0FVPjQbtC0CL+LI4kEnIM2UFu7giHqudzSAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}