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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd232d0664be2b58029f97a51e6edc7b2a5d253e22f4812ca61a82d6485109e2' 
  AND token = 'NdhB9tkAqO3k/sWJAZKWhwdBVGSHb6MjBbyyDfAbJjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}