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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c2aaf474476fd1dd42f03f285b22207d0f10d1943d3626f524f40f405cb2375' 
  AND token = 'nXYian2DWB6H9HzuUCdAdbo9XurqxRIEdRRhtuTimDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}